| County | Treated Streams |
|---|
| Adams | Conewago Creek |
| Armstrong | Allegheny River, Kiskiminetas River, Mahoning Creek, Redbank Creek |
| Berks | Manatawny Creek, Schuylkill River, Tulpehocken Creek |
| Bradford | Chemung River, North Branch Susquehanna River |
| Bucks | Delaware River, Tohickon Creek |
| Cambria | Conemaugh River |
| Chester | Brandywine Creek, French Creek, Octoraro Creek, Schuylkill River |
| Clarion | Allegheny River, Clarion River, Redbank Creek |
| Clinton | Bald Eagle Creek, West Branch Susquehanna River |
| Columbia | Fishing Creek, North Branch Susquehanna River |
| Cumberland | Conodoguinet Creek, Susquehanna River, Yellow Breeches Creek |
| Dauphin | Juniata River, Mahantango Creek, Susquehanna River, Swatara Creek |
| Elk | Clarion River |
| Fayette | Youghiogheny River |
| Forest | Allegheny River, Clarion River, Tionesta Creek |
| Huntingdon | Aughwick Creek, Frankstown Branch Juniata River, Juniata River |
| Indiana | Conemaugh River, Kiskiminetas River |
| Juniata | Juniata River, Susquehanna River, Tuscarora Creek |
| Lackawanna | North Branch Susquehanna River |
| Lawrence | Connoquenessing Creek, Neshannock Creek, Slippery Rock Creek |
| Lehigh | Lehigh River |
| Luzerne | North Branch Susquehanna River |
| Lycoming | Loyalsock Creek, Pine Creek, West Branch Susquehanna River |
| Mifflin | Juniata River |
| Montgomery | Manatawny Creek, Perkiomen Creek, Schuylkill River |
| Northampton | Delaware River, Lehigh River |
| Perry | Juniata River, Sherman Creek, Susquehanna River |
| Schuylkill | Schuylkill River |
| Snyder | Middle Creek, Penns Creek, Susquehanna River |
| Union | Penns Creek, West Branch Susquehanna River |
| Venango | Allegheny River, French Creek, Oil Creek, Sandy Creek, Sugar Creek |
| Warren | Allegheny River, Brokenstraw Creek, Conewango Creek |
| Westmoreland | Conemaugh River, Kiskiminetas River, Loyalhanna Creek, Youghiogheny River |
| Wyoming | North Branch Susquehanna River, Tunkhannock Creek |
| York | Conewago Creek, Susquehanna River, Yellow Breeches Creek |